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Alpha-2C adrenergic receptor

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

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Alpha-2C adrenergic receptor

Also known as Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR).
ADRA2C: Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 4p16

Cellular Component: cytoplasm; endosome; integral to plasma membrane; plasma membrane

Molecular Function: alpha-2A adrenergic receptor binding; alpha2-adrenergic receptor activity; epinephrine binding; protein binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: activation of protein kinase B; cell-cell signaling; G-protein coupled receptor protein signaling pathway; positive regulation of neuron differentiation; regulation of insulin secretion

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