Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
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ADRA2C: Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 4p16
Cellular Component: cytoplasm; endosome; integral to plasma membrane; plasma membrane
Molecular Function: alpha-2A adrenergic receptor binding; alpha2-adrenergic receptor activity; epinephrine binding; protein binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: activation of protein kinase B; cell-cell signaling; G-protein coupled receptor protein signaling pathway; positive regulation of neuron differentiation; regulation of insulin secretion
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