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Alpha-internexin

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity).

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Alpha-internexin

Also known as Alpha-internexin (Alpha-Inx).
INA: Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges. Belongs to the intermediate filament family.

Protein type: Cytoskeletal

Cellular Component: extracellular space; intermediate filament cytoskeleton; myelin sheath; neurofilament; nuclear membrane; nucleoplasm

Molecular Function: protein binding; protein heterodimerization activity

Biological Process: intermediate filament cytoskeleton organization and biogenesis; neurofilament cytoskeleton organization and biogenesis; substantia nigra development; tissue regeneration
Proteins Root Name Listing
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