Inhibits sodium channels (Nav) inactivation. Shows two types of inhibitory activities on channels. Inhibition of hNav1.6/SCN8A shows a large increase in the steady-state current component without any increase in the slow component, whereas inhibition of hNav1.1/SCN1A, hNav1.2/SCN2A, hNav1.3/SCN3A and hNav1.7/SCN9A shows a large increase in the slow component with only a small steady-state component . Is 5-fold less potent than beta-PMTX for inducing repetitive action potentials in lobster neuromuscular junctions.
Below are the list of possible Alpha-pompilidotoxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.