• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Aly/REF export factor

Export adapter involved in spliced and unspliced mRNA nuclear export. Binds mRNA which is transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway); enhances NXF1-NXT1 RNA-binding activity.

Below are the list of possible Aly/REF export factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Aly/REF export factor 2

Also known as Aly/REF export factor 2 (Alyref) (RNA and export factor-binding protein 2).
Refbp2: Acts as chaperone and promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains and thereby promotes transcriptional activation. Plays a role in mRNA processing and export. May function as scaffold that mediates interactions between proteins and/or RNA. Integral part of the THO/TREX complex that is recruited to transcribed genes and travels with the RNA polymerase during elongation. Is part of the exon junction complex that remains associated with spliced mRNA and plays an important role in mRNA export and nonsense-mediated RNA decay. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; RNA-binding

Molecular Function: RNA binding; single-stranded DNA binding

Biological Process: mRNA transport

Go back to Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000