Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis.
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Amiloride-sensitive amine oxidase [copper-containing] Recombinant
Amiloride-sensitive amine oxidase [copper-containing] Antibody
ABP1: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Belongs to the copper/topaquinone oxidase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - histidine; Amino Acid Metabolism - tryptophan; EC 184.108.40.206; Oxidoreductase; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; plasma membrane; tight junction
Molecular Function: amine oxidase activity; calcium ion binding; copper ion binding; drug binding; heparin binding; protein complex binding; protein homodimerization activity; quinone binding; receptor activity; zinc ion binding
Biological Process: amiloride transport; response to antibiotic; response to drug