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Amphoterin-induced protein

Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.

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Amphoterin-induced protein 1

Also known as Amphoterin-induced protein 1 (AMIGO-1) (Alivin-2).
AMIGO1: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Belongs to the immunoglobulin superfamily. AMIGO family.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: dendrite; voltage-gated potassium channel complex

Molecular Function: potassium channel regulator activity

Biological Process: axonal fasciculation; heterophilic cell adhesion; homophilic cell adhesion; myelination; positive regulation of axonogenesis

Amphoterin-induced protein 2

Also known as Amphoterin-induced protein 2 (AMIGO-2).
Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain ().

Amphoterin-induced protein 3

Also known as Amphoterin-induced protein 3 (AMIGO-3) (Alivin-3).
AMIGO3: May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain. Belongs to the immunoglobulin superfamily. AMIGO family.

Protein type: Membrane protein, integral

Cellular Component: integral to membrane

Biological Process: cell adhesion; heterophilic cell adhesion; nervous system development; positive regulation of synaptogenesis
Proteins Root Name Listing
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