• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Angiopoietin-related protein

Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787).

Below are the list of possible Angiopoietin-related protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Angiopoietin-related protein 1

Also known as Angiopoietin-related protein 1 (Angiopoietin-3) (ANG-3) (Angiopoietin-like protein 1).
ANGPTL1:

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: extracellular space

Angiopoietin-related protein 2

Also known as Angiopoietin-related protein 2 (Angiopoietin-like protein 2).
ANGPTL2: Induces sprouting in endothelial cells through an autocrine and paracrine action.

Protein type: Secreted; Secreted, signal peptide

Angiopoietin-related protein 3

Also known as Angiopoietin-related protein 3 (Angiopoietin-5) (ANG-5) (Angiopoietin-like protein 3).
ANGPTL3: Defects in ANGPTL3 are the cause of familial hypobetalipoproteinemia type 2 (FHBL2); also called combined hypobetalipoproteinemia familial. FHBL2 is a disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Affected individuals present with combined hypolipidemia, consisting of extremely low plasma levels of LDL cholesterol, HDL cholesterol, and triglycerides.

Protein type: Cell adhesion; Inhibitor; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: cell surface; extracellular space

Molecular Function: enzyme inhibitor activity; growth factor activity; integrin binding; phospholipase inhibitor activity

Biological Process: acylglycerol homeostasis; artery morphogenesis; cell-matrix adhesion; cholesterol homeostasis; cholesterol metabolic process; fatty acid metabolic process; glycerol metabolic process; lipid homeostasis; negative regulation of lipoprotein lipase activity; phospholipid catabolic process; phospholipid homeostasis; phospholipid metabolic process; positive regulation of angiogenesis; positive regulation of cell migration; positive regulation of lipid catabolic process; sequestering of lipid; signal transduction

Disease: Hypobetalipoproteinemia, Familial, 2

Angiopoietin-related protein 4

Also known as Angiopoietin-related protein 4 (425O18-1) (Angiopoietin-like protein 4) (Fasting-induced adipose factor) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Secreted protein Bk89).
ANGPTL4: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Protein type: Apoptosis; Extracellular matrix; Inhibitor; Secreted; Secreted, signal peptide

Cellular Component: extracellular region; extracellular space

Molecular Function: enzyme inhibitor activity; identical protein binding

Biological Process: negative regulation of apoptosis; negative regulation of lipoprotein lipase activity; protein homooligomerization

Angiopoietin-related protein 6

Also known as Angiopoietin-related protein 6 (Angiopoietin-like protein 6) (Angiopoietin-related growth factor).
ANGPTL6: May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: secretory granule

Angiopoietin-related protein 7

Also known as Angiopoietin-related protein 7 (Angiopoietin-like factor) (Angiopoietin-like protein 7) (Cornea-derived transcript 6 protein).
ANGPTL7:

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36

Biological Process: response to oxidative stress
Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000