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Anion exchange protein

Plasma membrane anion exchange protein of wide distribution.

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Anion exchange protein 2

Also known as Anion exchange protein 2 (AE 2) (Anion exchanger 2) (Band 3-related protein 2) (B3RP-2) (Non-erythroid band 3-like protein) (Solute carrier family 4 member 2).
SLC4A2: Plasma membrane anion exchange protein of wide distribution. Belongs to the anion exchanger (TC 2.A.31) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Cellular Component: apical plasma membrane; basolateral plasma membrane; focal adhesion; integral to plasma membrane; membrane

Molecular Function: anion transmembrane transporter activity; chloride transmembrane transporter activity; enzyme binding

Biological Process: chloride transport; gut development; regulation of intracellular pH; spermatogenesis

Anion exchange protein 3

Also known as Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Anion exchanger 3 brain isoform) (Neuronal band 3-like protein) (Solute carrier family 4 member 3).
Plasma membrane anion exchange protein.

Anion exchange protein 4

Also known as Anion exchange protein 4 (AE 4) (Anion exchanger 4) (Sodium bicarbonate cotransporter 5) (Solute carrier family 4 member 9).
SLC4A9: Probable apical anion exchanger of the kidney cortex. Belongs to the anion exchanger (TC 2.A.31) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: anion transmembrane transporter activity; sodium:bicarbonate symporter activity

Biological Process: bicarbonate transport; regulation of intracellular pH

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