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Anti-Muellerian hormone type-2 receptor

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

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Anti-Muellerian hormone type-2 receptor

Also known as Anti-Muellerian hormone type-2 receptor (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (C14) (MIS type II receptor) (MISRII) (MRII).
MISR2: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

Protein type: EC 2.7.11.30; Kinase, protein; Membrane protein, integral; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; STKR family; TKL group; Type2 subfamily

Cellular Component: integral to plasma membrane

Molecular Function: hormone binding; receptor activity; transforming growth factor beta receptor activity, type II

Biological Process: female gonad development; G-protein coupled receptor protein signaling pathway; male gonad development; sex differentiation; signal transduction; transforming growth factor beta receptor signaling pathway

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