• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

AP-1-like transcription activator

Transcription activator closely related to YAP1. Like YAP1, its activity can be induced by cadmium and peroxide stress, probably involving similar mechanisms inducing nuclear accumulation and thus transcription activation. YAP2, like YAP1, preferentially binds to promoters with the core binding site 5'-TTA[CG]TAA-3', but does not activate transcription of genes known to be activated by YAP1 in response to oxidative stress (such as TRX2, SSA1, GSH1). It is still not clear whether it is involved in oxidative stress response. When overexpressed, it confers pleiotropic drug-resistance and increases cellular tolerance to cadmium, iron chelators and zinc.

Below are the list of possible AP-1-like transcription activator products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

AP-1-like transcription activator YAP2

Also known as AP-1-like transcription activator YAP2 (Cadmium resistance protein 1) (Transcription factor CAD1).
Transcription activator closely related to YAP1. Like YAP1, its activity can be induced by cadmium and peroxide stress, probably involving similar mechanisms inducing nuclear accumulation and thus transcription activation. YAP2, like YAP1, preferentially binds to promoters with the core binding site 5'-TTA[CG]TAA-3', but does not activate transcription of genes known to be activated by YAP1 in response to oxidative stress (such as TRX2, SSA1, GSH1). It is still not clear whether it is involved in oxidative stress response. When overexpressed, it confers pleiotropic drug-resistance and increases cellular tolerance to cadmium, iron chelators and zinc.

Go back to Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000