• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Apelin receptor

Receptor for an apelin-like peptide coupled to G proteins that inhibit adenylate cyclase activity. Required for cardiovascular development, particularly for intersomitic vein angiogenesis. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone. Acts upstream of the i/o type of G-alpha proteins in the differentiation of endothelium, erythroid cells, myeloid cells and cardiomyocytes (By similarity).

Below are the list of possible Apelin receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Apelin receptor

Also known as Apelin receptor (Angiotensin receptor-like 1) (Angiotensin receptor-related protein) (G-protein coupled receptor APJ).
Receptor for an apelin-like peptide coupled to G proteins that inhibit adenylate cyclase activity. Required for cardiovascular development, particularly for intersomitic vein angiogenesis. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone. Acts upstream of the i/o type of G-alpha proteins in the differentiation of endothelium, erythroid cells, myeloid cells and cardiomyocytes ().

Apelin receptor A

Also known as Apelin receptor A (Angiotensin II receptor-like 1a) (Angiotensin receptor-like 1a) (G-protein coupled receptor APJ A).
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:24316148, PubMed:24407481). Acts redundantly with agtrl1b in heart development.

Apelin receptor B

Also known as Apelin receptor B (Angiotensin II receptor-like 1b) (Angiotensin receptor-like 1b) (G-protein coupled receptor APJ B) (Protein grinch).
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:24316148, PubMed:24407481). Acts redundantly with agtrl1a in heart development.
Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000