Hormone required during early development for endoderm differentiation and heart morphogenesis by acting as a ligand for the apelin receptor (APLNR). Acts as a motogen by promoting endoderm and mesendoderm cell migration during gastrulation by binding and activating the apelin receptor, thereby driving internalization of the apelin receptor. Plays a key role during heart development by acting as a ligand for the apelin receptor (By similarity).
Below are the list of possible Apelin receptor early endogenous ligand products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
Apelin receptor early endogenous ligand Recombinant
Apelin receptor early endogenous ligand Antibody
APELA: Hormone required for endoderm differentiation and heart morphogenesis. Acts as a ligand for the apelin receptor (APLNR) during heart development. Belongs to the Elabela family. Interacts with APLNR
Chromosomal Location of Human Ortholog: 4q32
Cellular Component: extracellular region
Molecular Function: apelin receptor binding; hormone activity
Biological Process: apelin receptor signaling pathway; endoderm development; heart development