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Apoptosis-enhancing nuclease

Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis (By similarity).

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Apoptosis-enhancing nuclease

Also known as Apoptosis-enhancing nuclease (Interferon-stimulated 20 kDa exonuclease-like 1).
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis ().
Proteins Root Name Listing
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