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Apoptosis-resistant E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation.

Below are the list of possible Apoptosis-resistant E3 ubiquitin protein ligase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Apoptosis-resistant E3 ubiquitin protein ligase 1

Also known as Apoptosis-resistant E3 ubiquitin protein ligase 1 (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1).
AREL1: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: ubiquitin-protein ligase activity

Biological Process: negative regulation of apoptosis; protein ubiquitination during ubiquitin-dependent protein catabolic process
Proteins Root Name Listing
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