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Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration (By similarity).

Below are the list of possible Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

Also known as Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1) (Cnt-b1).
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration ().

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

Also known as Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2).
CENTB2: a member of the centaurin family of ADP-ribosylation factor directed GTPase-activating proteins. Regulates cytoskeletal and membrane trafficking events in the cell periphery. Binding of phosphoinositides to a pleckstrin homology domain may regulate subcellular localization and activity.

Protein type: GAPs; GAPs, ARF; Motility/polarity/chemotaxis

Cellular Component: endosome membrane; membrane; ruffle

Molecular Function: GTPase activator activity; protein binding; Rab GTPase binding

Biological Process: actin filament-based process

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

Also known as Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (Centaurin-beta-5) (Cnt-b5).
CENTB5: GTPase-activating protein for the ADP ribosylation factor family (Potential). 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, ARF; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: -

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