Sesquiterpene synthase involved in the biosynthesis of beta-caryophyllene, a sesquiterpene with anti-inflammatory and anti-carcinogenic activities. Can use farnesyl diphosphate and (+)-chrysanthemyl diphosphate as substrates, but not geranylgeranyl diphosphate. Produces two irregular monoterpenes, yomogi alcohol and artemisia alcohol from (+)-chrysanthemyl diphosphate. Limited activity with geranyl diphosphate, leading to the production of limonene, terpinolene, beta-pinene, gamma-terpinene, alpha-terpinene and other minor products.
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