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Estrogen sulfotransferase

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.

Below are the list of possible Estrogen sulfotransferase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Estrogen sulfotransferase

Also known as Estrogen sulfotransferase (EST-1) (Sulfotransferase 1E1) (ST1E1) (Sulfotransferase, estrogen-preferring).
SULT1E1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. Belongs to the sulfotransferase 1 family.

Protein type: EC 2.8.2.4; Energy Metabolism - sulfur; Lipid Metabolism - androgen and estrogen; Transferase

Chromosomal Location of Human Ortholog: 4q13.1

Cellular Component: cytosol

Molecular Function: aryl sulfotransferase activity; estrone sulfotransferase activity; flavonol 3-sulfotransferase activity; protein binding; steroid sulfotransferase activity; sulfotransferase activity

Biological Process: 3'-phosphoadenosine 5'-phosphosulfate metabolic process; estrogen metabolic process; positive regulation of fat cell differentiation; steroid metabolic process; sulfation

Estrogen sulfotransferase Ste2

Also known as Estrogen sulfotransferase Ste2 (Estrogen sulfotransferase, isoform 6) (EST-6) (Estrone sulfotransferase) (Sulfotransferase, estrogen-preferring).
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol ().

Estrogen sulfotransferase, isoform 1

Also known as Estrogen sulfotransferase, isoform 1 (EST-1) (Estrone sulfotransferase) (Sulfotransferase 1E1) (ST1E1) (Sulfotransferase, estrogen-preferring).
isozyme that catalyzes the sulfation of estrogens, including beta-estradiol and estrone, but not of dehydroepiandrosterone, pregnenolone, cortisol or testosterone; plays a role in estrogen metabolism [RGD, Feb 2006]

Estrogen sulfotransferase, isoform 2

Also known as Estrogen sulfotransferase, isoform 2 (EST-2) (Estrone sulfotransferase) (Sulfotransferase, estrogen-preferring).
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol ().

Estrogen sulfotransferase, isoform 3

Also known as Estrogen sulfotransferase, isoform 3 (EST-3) (Estrone sulfotransferase) (Sulfotransferase, estrogen-preferring).
SULT1E1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol (By similarity)

Protein type: EC 2.8.2.4; Energy Metabolism - sulfur; Lipid Metabolism - androgen and estrogen; Transferase

Molecular Function: estrone sulfotransferase activity; steroid sulfotransferase activity

Biological Process: estrogen metabolic process

Estrogen sulfotransferase, testis isoform

Also known as Estrogen sulfotransferase, testis isoform (Sulfotransferase 1E1) (ST1E1) (Sulfotransferase, estrogen-preferring).
SULT1E1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. Belongs to the sulfotransferase 1 family.

Protein type: EC 2.8.2.4; Energy Metabolism - sulfur; Lipid Metabolism - androgen and estrogen; Transferase

Cellular Component: cytoplasm

Molecular Function: flavonol 3-sulfotransferase activity; steroid sulfotransferase activity; sulfotransferase activity

Biological Process: estrogen metabolic process; female pregnancy; positive regulation of fat cell differentiation; sulfation

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