Mas-related G-protein coupled receptor
Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity).
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Mas-related G-protein coupled receptor member A
Mas-related G-protein coupled receptor member A1
Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception.
Mas-related G-protein coupled receptor member A2
Mas-related G-protein coupled receptor member A3
Mas-related G-protein coupled receptor member A4
MRGPRA4: Orphan receptor. May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Cellular Component: integral to plasma membrane
Molecular Function: neuropeptide receptor activity
Mas-related G-protein coupled receptor member A5
Mas-related G-protein coupled receptor member A6
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor member A7
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor member A8
Mas-related G-protein coupled receptor member B1
Mas-related G-protein coupled receptor member B2
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor member B3
Protein type: Membrane protein, integral
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor member B4
Mas-related G-protein coupled receptor member B5
Mas-related G-protein coupled receptor member B8
Mas-related G-protein coupled receptor member D
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) ().
Mas-related G-protein coupled receptor member E
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor member F
MRGPRF: Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: integral to plasma membrane; nuclear membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor member G
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor member H
Mas-related G-protein coupled receptor member X1
MRGPRX4: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: chemosensory behavior; hemopoietic progenitor cell differentiation
Mas-related G-protein coupled receptor member X2
Mas-related G-protein coupled receptor member X3
Mas-related G-protein coupled receptor member X4
MRGPRX4: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Mas-related G-protein coupled receptor MRG
MAS1L: Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 6p22.1
Cellular Component: cytoplasm; integral to plasma membrane; nucleoplasm; plasma membrane
Molecular Function: G-protein coupled receptor activity
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