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Probable importin

Active in protein import into the nucleus.

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Probable importin subunit alpha-A

Also known as Probable importin subunit alpha-A (Karyopherin subunit alpha-A).
Functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC). Binds specifically and directly to substrates containing either a simple or bipartite NLS motif ().

Probable importin subunit beta-4

Also known as Probable importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123).
Required for nuclear protein import, its predominant substrate seems to be ribosomal proteins. Binds to nucleoporins and the GTP-bound form of gsp1 (Ran) ().

Probable importin-5 homolog

Also known as Probable importin-5 homolog (Importin subunit beta-3) (Karyopherin beta-3).
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates ().

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