• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Selenoprotein

May be involved in a redox-related process. Required for survival and specifically for salivary gland morphogenesis.

Below are the list of possible Selenoprotein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Selenoprotein BthD

Also known as Selenoprotein BthD (dSelM).
May be involved in a redox-related process. Required for survival and specifically for salivary gland morphogenesis.

Selenoprotein H

Also known as Selenoprotein H (SelH).
SELH: May be involved in a redox-related process (Potential). Belongs to the SelWTH family.

Chromosomal Location of Human Ortholog: 11q12.1

Selenoprotein K

Also known as Selenoprotein K (SelK).
The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER stress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2016]

Selenoprotein M

May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation. Involved in the regulation of reproduction during the period of rapid gonadal development.

Selenoprotein N

Also known as Selenoprotein N (SelN).
SEPN1: Defects in SEPN1 are the cause of rigid spine muscular dystrophy 1 (RSMD1). A neuromuscular disorder characterized by poor axial muscle strength, scoliosis and neck weakness, and a variable degree of spinal rigidity. Early ventilatory insufficiency can lead to death by respiratory failure. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: endoplasmic reticulum membrane

Biological Process: alveolus development; calcium ion homeostasis; mitochondrion organization and biogenesis; multicellular organismal response to stress; positive regulation of skeletal muscle cell proliferation; respiratory system process; response to muscle activity involved in regulation of muscle adaptation; satellite cell compartment self-renewal involved in skeletal muscle regeneration; satellite cell differentiation; skeletal muscle fiber development; skeletal muscle regeneration

Selenoprotein P

Also known as Selenoprotein P (SeP).
SEPP1: Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. Belongs to the selenoprotein P family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space

Molecular Function: selenium binding

Biological Process: brain development; growth; locomotory behavior; post-embryonic development; response to selenium ion; selenium metabolic process; sexual reproduction

Selenoprotein Pa

Also known as Selenoprotein Pa (zSelPa).
Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium.

Selenoprotein Pb

Also known as Selenoprotein Pb (zSelPb).
Might be responsible for some of the extracellular antioxidant defense properties of selenium.

Selenoprotein S

Also known as Selenoprotein S (SelS) (Minor histocompatibility antigen H47) (VCP-interacting membrane protein).
SELS: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination. Belongs to the selenoprotein S family.

Protein type: Endoplasmic reticulum; Membrane protein, integral

Cellular Component: cytoplasmic microtubule; endoplasmic reticulum; integral to endoplasmic reticulum membrane

Molecular Function: antioxidant activity; ATPase binding; enzyme binding; protein binding

Biological Process: cell redox homeostasis; ER overload response; ER-associated protein catabolic process; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of inflammatory response; negative regulation of interleukin-6 production; negative regulation of nitric-oxide synthase biosynthetic process; negative regulation of tumor necrosis factor production; response to redox state; retrograde protein transport, ER to cytosol; unfolded protein response

Selenoprotein S A

Also known as Selenoprotein S A (SelS A) (VCP-interacting membrane protein).
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner ().

Selenoprotein S B

Also known as Selenoprotein S B (SelS B) (VCP-interacting membrane protein).
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner ().

Selenoprotein T

Also known as Selenoprotein T (SelT).
SELT: a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q25.1

Selenoprotein V

Also known as Selenoprotein V (SelV).
SELV: May be involved in a redox-related process (Potential). Belongs to the SelWTH family.

Chromosomal Location of Human Ortholog: 19q13.2

Molecular Function: protein binding

Selenoprotein W

Also known as Selenoprotein W (SelW).
Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency ().

Go back to Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000