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PROZ elisa kit :: Human vitamin K-dependent protein Z ELISA Kit

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Catalog # MBS701077
Unit / Price
  24-Strip-Wells (LIMIT 1)  /  $240 +1 FREE 8GB USB
  48-Strip-Wells  /  $550 +1 FREE 8GB USB
  96-Strip-Wells  /  $795 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

vitamin K-dependent protein Z (PROZ), ELISA Kit

Popular Item
Also Known As

Human vitamin K-dependent protein Z, PROZ ELISA Kit

Product Synonym Names
Human vitamin K-dependent protein Z (PROZ) ELISA kit; PZ; protein Z; vitamin K-dependent plasma glycoprotein; vitamin K-dependent protein Z
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS701077 Testing Data
Sequence Length
422
OMIM
176895
3D Structure
ModBase 3D Structure for P22891
Species Reactivity
Specificity
This assay has high sensitivity and excellent specificity for detection of Human PROZ. No significant cross-reactivity or interference between Human PROZ and analogues was observed.
Samples
Serum, plasma, tissue homogenates
Assay Type
Sandwich
Detection Range
125 ng/ml-8000 ng/ml
Sensitivity
31.25 ng/ml
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Detection Wavelength
450 nm
Sample Volume
50-100ul
Protein Biological Process 1
Blood Coagulation
Protein Biological Process 3
Blood coagulation
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PROZ elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forPROZpurchase
MBS701077 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the vitamin K-dependent protein Z (PROZ) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PROZ. The ELISA analytical biochemical technique of the MBS701077 kit is based on PROZ antibody-PROZ antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PROZ antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PROZ. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
PROZ elisa kit
For samples: For the quantitative determination of human protein Z concentrations in serum, plasma, tissue homogenates.

PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for protein Z has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any protein Z present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for protein Z is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of protein Z bound in the initial step. The color development is stopped and the intensity of the color is measured.

Typical Testing Data/Standard Curve (for reference only) of PROZ elisa kit
PROZ elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS701077. Click to request current manual
NCBI/Uniprot data below describe general gene information for PROZ. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,744 Da
NCBI Official Full Name
vitamin K-dependent protein Z isoform 1
NCBI Official Synonym Full Names
protein Z, vitamin K-dependent plasma glycoprotein
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
vitamin K-dependent protein Z
UniProt Protein Name
Vitamin K-dependent protein Z
UniProt Gene Name
UniProt Entry Name
PROZ_HUMAN
NCBI Summary for PROZ
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
UniProt Comments for PROZ
Function: Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withPROZ elisa kit
Organs/Tissues associated with PROZ elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with PROZ and Liver
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