• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PTPN5 recombinant protein :: Tyrosine-protein phosphatase non-receptor type 5 Recombinant Protein

Scan QR to view Datasheet
Catalog # MBS963965
Unit / Price
  0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $795 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $945 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,070 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,180 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,185 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,210 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,715 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,795 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,840 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,285 +2 FREE 8GB USB
SDS-PAGE
Product Name

Tyrosine-protein phosphatase non-receptor type 5 (PTPN5), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Tyrosine-protein phosphatase non-receptor type 5

Product Synonym Names
Neural-specific protein-tyrosine phosphatase; Striatum-enriched protein-tyrosine phosphatase; STEP
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS963965 COA
Sequence Positions
300-555. Partial.
Sequence Length
555
Sequence
LQAEFFEIPM NFVDPKEYDI PGLVRKNRYK TILPNPHSRV CLTSPDPDDP LSSYINANYI RGYGGEEKVY IATQGPIVST VADFWRMVWQ EHTPIIVMIT NIEEMNEKCT EYWPEEQVAY DGVEITVQKV IHTEDYRLRL ISLKSGTEER GLKHYWFTSW PDQKTPDRAP PLLHLVREVE EAAQQEGPHC APIIVHCSAG IGRTGCFIAT SICCQQLRQE GVVDILKTTC QLRQDRGGMI QTCEQYQFVH HVMSLY
OMIM
176879
3D Structure
ModBase 3D Structure for P54829
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of PTPN5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PTPN5 recombinant protein
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
Product Categories/Family for PTPN5 recombinant protein

PTPN5 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for PTPN5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45.4kD
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 5 isoform b
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 5
NCBI Official Symbol
PTPN5  [Similar Products]
NCBI Official Synonym Symbols
STEP; PTPSTEP
  [Similar Products]
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 5
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 5
UniProt Synonym Protein Names
Neural-specific protein-tyrosine phosphatase; Striatum-enriched protein-tyrosine phosphatase; STEP
UniProt Gene Name
PTPN5  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
PTN5_HUMAN
UniProt Comments for PTPN5
STEP: a non-receptor protein-tyrosine phosphatase. STEP (striatum enriched phosphatase) Contains a single phosphatase catalytic domain located at the C-terminus. Two alternatively-spliced messages have been described.

Protein type: Membrane protein, multi-pass; EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: axon; cytosol; endoplasmic reticulum membrane; integral to membrane; perikaryon

Molecular Function: glutamate receptor binding; mitogen-activated protein kinase binding; phosphotyrosine binding; protein binding; protein tyrosine phosphatase activity

Biological Process: negative regulation of MAP kinase activity; positive regulation of protein amino acid phosphorylation; positive regulation of protein import into nucleus, translocation; positive regulation of receptor internalization; protein amino acid dephosphorylation; response to amphetamine; response to drug
Product References and Citations for PTPN5 recombinant protein
Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004) The full-ORF clone resource of the German cDNA consortium.Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.BMC Genomics 8:399-399(2007) Human chromosome 11 DNA sequence and analysis including novel gene identification.Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G., Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.Nature 440:497-500(2006)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000