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PTX3 elisa kit :: Human PTX3 ELISA Kit

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Catalog # MBS825009
Unit / Price
  96 Tests  /  $470 +1 FREE 8GB USB
 Typical Testing Data/Standard Curve (for reference only)
Product Name

PTX3, ELISA Kit

Popular Item
Full Product Name

Human PTX3 ELISA Kit

Product Synonym Names
TNFAIP5; TSG14; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
602492
3D Structure
ModBase 3D Structure for P26022
Species Reactivity
Specificity
The Human PTX3 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human PTX3 proteins within the range of 312 pg/ml - 20000 pg/ml.
Samples
Cell Culture Supernatants, Serum, Plasma
Assay Type
Quantitative Sandwich
Sensitivity
<10 pg/ml.
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PTX3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forPTX3purchase
MBS825009 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PTX3, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTX3. The ELISA analytical biochemical technique of the MBS825009 kit is based on PTX3 antibody-PTX3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTX3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTX3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
PTX3 elisa kit
Principle of the Assay: MBS Human PTX3 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human PTX3 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human PTX3 coated on a 96-well plate. Standards and samples are pipetted into the wells and PTX3 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human PTX3 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of PTX3 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.

Background: PTX3 (Pentraxin 3) is a member of the pentraxin superfamily. This super family characterized by cyclic multimeric structure. The PTX3 gene is mapped to 3q25.32. The predicted 381-amino acid PTX3 protein has homology to the pentraxin protein family. Significant levels of PTX3 were detected in plasma of neutropenic patients with systemic A. PTX3 is effective in preventing CMV infection and reactivation, as well as subsequent Aspergillus infection. PTX3 activates the classical pathway of complementactivation and facilitates pathogen recognition by macrophages and DCs.
Applications Tested/Suitable for PTX3 elisa kit
Sandwich ELISA (SE)

Typical Testing Data/Standard Curve (for reference only) of PTX3 elisa kit
PTX3 elisa kit  Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS825009. Click to request current manual
NCBI/Uniprot data below describe general gene information for PTX3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,976 Da
NCBI Official Full Name
pentraxin-related protein PTX3
NCBI Official Synonym Full Names
pentraxin 3, long
NCBI Official Symbol
NCBI Official Synonym Symbols
TSG-14; TNFAIP5
  [Similar Products]
NCBI Protein Information
pentraxin-related protein PTX3; pentraxin-3; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor necrosis factor-inducible gene 14 protein; pentraxin-related gene, rapidly induced by IL-1 beta; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
UniProt Protein Name
Pentraxin-related protein PTX3
UniProt Synonym Protein Names
Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14  [Similar Products]
UniProt Entry Name
PTX3_HUMAN
UniProt Comments for PTX3
PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q25

Cellular Component: extracellular space; extracellular region

Molecular Function: complement component C1q binding; zymosan binding; virion binding

Biological Process: positive regulation of nitric oxide biosynthetic process; negative regulation of virion penetration into host cell; positive regulation of phagocytosis; innate immune response; response to yeast; opsonization; inflammatory response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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