NP_004151.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,145 Da
NCBI Official Full Name
peptide YY preproprotein
NCBI Official Synonym Full Names
peptide YY
NCBI Official Synonym Symbols
NCBI Protein Information
peptide YY; prepro-PYY; peptide tyrosine tyrosine
UniProt Protein Name
Peptide YY
UniProt Synonym Protein Names
PYY-I; Peptide tyrosine tyrosineCleaved into the following chain:Peptide YY(3-36); Alternative name(s):; PYY-II
UniProt Synonym Gene Names
UniProt Entry Name
PYY_HUMAN
NCBI Summary for PYY
The protein encoded by this gene is proteolytically processed to release a peptide that inhibits pancreatic secretion and mobility in the gut. Rare variations in this gene could increase susceptibility to obesity. [provided by RefSeq, Jul 2010]
UniProt Comments for PYY
PYY: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: extracellular space; extracellular region
Molecular Function: neuropeptide hormone activity; protein binding; G-protein-coupled receptor binding; hormone activity
Biological Process: cell proliferation; G-protein coupled receptor protein signaling pathway; cell-cell signaling; eating behavior; neuropeptide signaling pathway; digestion; regulation of appetite; feeding behavior; cytoskeleton organization and biogenesis; cell motility
Disease: Obesity
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Products associated with PYY elisa kit
Pathways associated with PYY elisa kit
Diseases associated with PYY elisa kit
Organs/Tissues associated with PYY elisa kit
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