NP_001186499.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,560 Da
NCBI Official Full Name
CAP-Gly domain-containing linker protein 3
NCBI Official Synonym Full Names
CAP-GLY domain containing linker protein 3
NCBI Protein Information
CAP-Gly domain-containing linker protein 3; restin-like 1; CLIP-170-related 59 kDa protein; cytoplasmic linker protein 170-related 59 kDa protein
UniProt Protein Name
CAP-Gly domain-containing linker protein 3
UniProt Synonym Protein Names
Cytoplasmic linker protein 170-related 59 kDa protein; CLIP-170-related 59 kDa protein; CLIPR-59
UniProt Synonym Gene Names
UniProt Entry Name
CLIP3_HUMAN
NCBI Summary for CLIP3
This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
UniProt Comments for CLIP3
CLIPR-59: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 19q13.12
Cellular Component: Golgi stack; recycling endosome membrane; early endosome membrane; plasma membrane; trans-Golgi network membrane; trans-Golgi network; lipid raft
Molecular Function: microtubule binding
Biological Process: peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine; fat cell differentiation; positive regulation of apoptosis; negative regulation of microtubule polymerization; positive regulation of endocytosis; positive regulation of protein amino acid phosphorylation
Research Articles on CLIP3
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Diseases associated with CLIP3 elisa kit
Organs/Tissues associated with CLIP3 elisa kit
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