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anti-Rac1 antibody :: Rac1 Antibody

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Catalog # MBS8511721
Unit / Price
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  0.1 mg  /  $290 +1 FREE 8GB USB
anti-Rac1 antibody
Product Name

Rac1, Antibody

Popular Item
Full Product Name

Rac1 Antibody

Product Synonym Names
Ras-like protein TC25; Ras-related C3 botulinum toxin substrate 1; p21-Rac1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602048
3D Structure
ModBase 3D Structure for P63000
Species Reactivity
Human, Mouse, Rat
Specificity
Rac1 antibody detects endogenous levels of total Rac1
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human Rac1
Preparation and Storage
Store at-20 degree C for 1 year
Other Notes
Small volumes of anti-Rac1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Rac1 antibody
Rac1 encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
Applications Tested/Suitable for anti-Rac1 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-Rac1 antibody
WB: 1:500~1:1000
IF: 1:200
NCBI/Uniprot data below describe general gene information for Rac1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26 kd
NCBI Official Full Name
ras-related C3 botulinum toxin substrate 1 isoform Rac1
NCBI Official Synonym Full Names
Rac family small GTPase 1
NCBI Official Symbol
NCBI Official Synonym Symbols
MIG5; MRD48; Rac-1; TC-25; p21-Rac1
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NCBI Protein Information
ras-related C3 botulinum toxin substrate 1
UniProt Protein Name
Ras-related C3 botulinum toxin substrate 1
UniProt Synonym Protein Names
Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NCBI Summary for Rac1
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt Comments for Rac1
Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In glioma cells, promotes cell migration and invasion. In podocytes, promotes nuclear shuttling of NR3C2; this modulation is required for a proper kidney functioning. Required for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. In synapses, seems to mediate the regulation of F-actin cluster formation performed by SHANK3.
Research Articles on Rac1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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