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RAC3 recombinant protein

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Catalog # MBS203763
Unit / Price
  0.1 mg  /  $310 +1 FREE 8GB USB
  0.5 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

RAC3, Recombinant Protein

Also Known As

RAC3, 1-189aa, Human, E Coli

Product Synonym Names
ras-related C3 botulinum toxin substrate 3; p21-Rac3; Rac1B; RAS related C3 botulinum substrate 3; Ras related C3 botulinum toxin substrate 3; rho family small GTP binding protein Rac3; Rho family small GTP binding protein Rac3; RP23-84C12.18
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
192
Sequence
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPHTPI LLVGTKLDLR DDKDTIERLR DKKLAPITYP QGLAMAREIG SVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKPGKKC
OMIM
AF008591 mRNA
3D Structure
ModBase 3D Structure for P60763
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 200mM NaCl, 0.1mM PMSF, 1mM EDTA
Concentration
0.5 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of RAC3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RAC3 recombinant protein
RAC3 is a member of the Rac subfamily of the Rho small G proteins. This protein is a small (~21 kDa) monomeric GTP-binding protein, and is an important component of intracellular signalling pathway, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Recombinant human RAC3 protein was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for RAC3 recombinant protein
Applications Tested/Suitable for RAC3 recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for RAC3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21kDa (189aa), confirmed by MALDI-TOF
NCBI Official Full Name
ras-related C3 botulinum toxin substrate 3 isoform 1
NCBI Official Synonym Full Names
Rac family small GTPase 3
NCBI Official Symbol
NCBI Protein Information
ras-related C3 botulinum toxin substrate 3
UniProt Protein Name
Ras-related C3 botulinum toxin substrate 3
UniProt Synonym Protein Names
p21-Rac3
UniProt Gene Name
NCBI Summary for RAC3
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
UniProt Comments for RAC3
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Product References and Citations for RAC3 recombinant protein
De Langhe S., et al. (2002) Int. J. Mol. Med. 9:451-459; Haataja L, et al. (1997) J. Biol. Chem. 272 (33): 20384-88.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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