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RACGAP1 cdna clone

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Catalog # MBS1266440
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
RACGAP1 cdna clone
Product Name

RACGAP1, cDNA Clone

Popular Item
Full Product Name

RACGAP1 cDNA Clone

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggatacta tgatgctgaa tgtgcggaat ctgtttgagc agcttgtgcg ccgggtggag attctcagtg aaggaaatga agtccaattt atccagttgg cgaaggactt tgaggatttc cgtaaaaagt ggcagaggac tgaccatgag ctggggaaat acaaggatct tttgatgaaa gcagagactg agcgaagtgc tctggatgtt aagctgaagc atgcacgtaa tcaggtggat gtagagatca aacggagaca gagagctgag gctgactgcg aaaagctgga acgacagatt cagctgattc gagagatgct catgtgtgac acatctggca gcattcaact aagcgaggag caaaaatcag ctctggcttt tctcaacaga ggccaaccat ccagcagcaa tgctgggaac aaaagactat caaccattga tgaatctggt tccattttat cagatatcag ctttgacaag actgatgaat cactggattg ggactcttct ttggtgaaga ctttcaaact gaagaagaga gaaaagaggc gctctactag ccgacagttt gttgatggtc cccctggacc tgtaaagaaa actcgttcca ttggctctgc agtagaccag gggaatgaat ccatagttgc aaaaactaca gtgactgttc ccaatgatgg cgggcccatc gaagctgtgt ccactattga gactgtgcca tattggacca ggagccgaag gaaaacaggt actttacaac cttggaacag tgactccacc ctgaacagca ggcagctgga gccaagaact gagacagaca gtgtgggcac gccacagagt aatggaggga tgcgcctgca tgactttgtt tctaagacgg ttattaaacc tgaatcctgt gttccatgtg gaaagcggat aaaatttggc aaattatctc tgaagtgtcg agactgtcgt gtggtctctc atccagaatg tcgggaccgc tgtccccttc cctgcattcc taccctgata ggaacacctg tcaagattgg agagggaatg ctggcagact ttgtgtccca gacttctcca atgatcccct ccattgttgt gcattgtgta aatgagattg agcaaagagg tctgactgag acaggcctgt ataggatctc tggctgtgac cgcacagtaa aagagctgaa agagaaattc ctcagagtga aaactgtacc cctcctcagc aaagtggatg atatccatgc tatctgtagc cttctaaaag actttcttcg aaacctcaaa gaacctcttc tgacctttcg ccttaacaga gcctttatgg aagcagcaga aatcacagat gaagacaaca gcatagctgc catgtaccaa gctgttggtg aactgcccca ggccaacagg gacacattag ctttcctcat gattcacttg cagagagtgg ctcagagtcc acatactaaa atggatgttg ccaatctggc taaagtcttt ggccctacaa tagtggccca tgctgtgccc aatccagacc cagtgacaat gttacaggac atcaagcgtc aacccaaggt ggttgagcgc ctgctttcct tgcctctgga gtattggagt cagttcatga tggtggagca agagaacatt gaccccctac atgtcattga aaactcaaat gccttttcaa caccacagac accagatatt aaagtgagtt tactgggacc tgtgaccact cctgaacatc agcttctcaa gactccttca tctagttccc tgtcacagag agtccgttcc accctcacca agaacactcc tagatttggg agcaaaagca agtctgccac taacctagga cgacaaggca acttttttgc ttctccaatg ctcaagtga
OMIM
604980
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of RACGAP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for RACGAP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
71,027 Da
NCBI Official Full Name
Homo sapiens Rac GTPase activating protein 1, mRNA
NCBI Official Synonym Full Names
Rac GTPase activating protein 1
NCBI Official Symbol
RACGAP1  [Similar Products]
NCBI Official Synonym Symbols
CYK4; ID-GAP; HsCYK-4; MgcRacGAP
  [Similar Products]
NCBI Protein Information
rac GTPase-activating protein 1
UniProt Protein Name
Rac GTPase-activating protein 1
UniProt Synonym Protein Names
Male germ cell RacGap; MgcRacGAP; Protein CYK4 homolog; CYK4; HsCYK-4
UniProt Gene Name
RACGAP1  [Similar Products]
UniProt Synonym Gene Names
MgcRacGAP; CYK4; HsCYK-4  [Similar Products]
UniProt Entry Name
RGAP1_HUMAN
NCBI Summary for RACGAP1
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]
UniProt Comments for RACGAP1
MgcRacGAP: a rac GTPase activating protein. Plays an important role in cytokinesis by regulating cortical movement through RhoA. Phosphorylation by Aurora B apparently induces GAP activity toward RhoA.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: cleavage furrow; cytoplasm; cytosol; extrinsic to internal side of plasma membrane; midbody; nucleoplasm; nucleus; spindle midzone

Molecular Function: alpha-tubulin binding; beta-tubulin binding; gamma-tubulin binding; GTPase activator activity; microtubule binding; phosphatidylinositol-3,4,5-triphosphate binding; protein binding; protein kinase binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokinesis after mitosis; cytokinesis, contractile ring formation; embryonic development; microtubule-based movement; neuroblast proliferation; positive regulation of cytokinesis; regulation of attachment of spindle microtubules to kinetochore; regulation of small GTPase mediated signal transduction; retrograde vesicle-mediated transport, Golgi to ER; spermatogenesis; spindle midzone assembly involved in mitosis; sulfate transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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