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RALA elisa kit :: Human v-ral simian leukemia viral oncogene homolog A (ras related) ELISA Kit

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Catalog # MBS9330319
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
RALA elisa kit
Product Name

v-ral simian leukemia viral oncogene homolog A (ras related) (RALA), ELISA Kit

Popular Item
Also Known As

Human Ras-related protein Ral-A, RALA ELISA Kit

Product Synonym Names
Human Ras-related protein Ral-A (RALA) ELISA kit; MGC48949; RAL; RAS-like protein A; Ras family small GTP binding protein RALA; Ras-related protein Ral-A; ras related v-ral simian leukemia viral oncogene homolog A; v-ral simian leukemia viral oncogene homolog A (ras related)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
179550
3D Structure
ModBase 3D Structure for P11233
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
undiluted original Human body fluids, tissue homogenates, secretions or feces samples
Assay Type
Quantitative Sandwich
Detection Range
0.625 ng/ml - 20 ng/mL
Sensitivity
0.1 ng/mL
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of RALA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forRALApurchase
MBS9330319 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the v-ral simian leukemia viral oncogene homolog A (ras related) (RALA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RALA. The ELISA analytical biochemical technique of the MBS9330319 kit is based on RALA antibody-RALA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RALA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RALA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
RALA elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RALA (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9330319. Click to request current manual
NCBI/Uniprot data below describe general gene information for RALA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,567 Da
NCBI Official Full Name
ras-related protein Ral-A
NCBI Official Synonym Full Names
v-ral simian leukemia viral oncogene homolog A (ras related)
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
ras-related protein Ral-A; RAS-like protein A; ras related GTP binding protein A; Ras family small GTP binding protein RALA
UniProt Protein Name
Ras-related protein Ral-A
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
RALA_HUMAN
NCBI Summary for RALA
The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for RALA
RALA: Multifuntional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin- dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells. Interacts with RALBP1 via its effector domain. Interacts with EXOC8 and EXOC2. EXOC2 and EXOC8 have overlapping binding sites and compete for RALA binding. Interacts with Clostridium exoenzyme C3. Interacts with RALGPS1. Interacts with LPAR1 and LPAR2. Interacts with ADRBK1 in response to LPAR1 activation. RALA and ADRBK1 mutually inhibit each other's binding to LPAR1. Activated in an LPA-dependent manner by LPAR1 and in an LPA-independent manner by LPAR2. Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase- activating protein (GAP). Belongs to the small GTPase superfamily. Ras family.

Protein type: Motility/polarity/chemotaxis; G protein; G protein, monomeric; G protein, monomeric, Ras

Chromosomal Location of Human Ortholog: 7p15-p13

Cellular Component: cell surface; focal adhesion; cytoplasmic vesicle membrane; endocytic vesicle; plasma membrane; midbody; cleavage furrow

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin binding; Edg-2 lysophosphatidic acid receptor binding; ubiquitin protein ligase binding; ATPase binding

Biological Process: positive regulation of filopodium formation; regulation of exocytosis; exocytosis; lipid raft localization; viral reproduction; nerve growth factor receptor signaling pathway; metabolic process; actin cytoskeleton reorganization; Ras protein signal transduction; cytokinesis; chemotaxis; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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