AAA52692.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,931 Da
NCBI Official Full Name
retinoic acid receptor gamma
NCBI Official Synonym Full Names
retinoic acid receptor gamma
NCBI Official Synonym Symbols
NCBI Protein Information
retinoic acid receptor gamma
UniProt Protein Name
Retinoic acid receptor gamma
UniProt Synonym Protein Names
Nuclear receptor subfamily 1 group B member 3
UniProt Synonym Gene Names
UniProt Entry Name
RARG_HUMAN
NCBI Summary for RARgamma
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Comments for RARgamma
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function ().
Research Articles on RARgamma
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Products associated with RARgamma elisa kit
Pathways associated with RARgamma elisa kit
Diseases associated with RARgamma elisa kit
Organs/Tissues associated with RARgamma elisa kit
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