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RASGRF2 elisa kit :: Human Ras protein-specific guanine nucleotide-releasing factor 2 ELISA Kit

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Catalog # MBS9333238
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
RASGRF2 elisa kit
Product Name

Ras protein-specific guanine nucleotide-releasing factor 2 (RASGRF2), ELISA Kit

Popular Item
Also Known As

Human Ras-specific guanine nucleotide-releasing factor 2, RASGRF2 ELISA Kit

Product Synonym Names
Human Ras-specific guanine nucleotide-releasing factor 2 (RASGRF2) ELISA kit; DKFZp781H1715; GRF2; RAS-GRF2; ; Ras protein-specific guanine nucleotide-releasing factor 2
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
606614
3D Structure
ModBase 3D Structure for O14827
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Body fluids, tissue homogenates, secretions or feces samples
Assay Type
Quantitative Sandwich
Detection Range
0.25 ng/ml - 8 ng/ml
Sensitivity
0.1 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of RASGRF2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forRASGRF2purchase
MBS9333238 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ras protein-specific guanine nucleotide-releasing factor 2 (RASGRF2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RASGRF2. The ELISA analytical biochemical technique of the MBS9333238 kit is based on RASGRF2 antibody-RASGRF2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RASGRF2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RASGRF2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
RASGRF2 elisa kit
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RASGRF2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9333238. Click to request current manual
NCBI/Uniprot data below describe general gene information for RASGRF2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
140,764 Da
NCBI Official Full Name
ras-specific guanine nucleotide-releasing factor 2
NCBI Official Synonym Full Names
Ras protein-specific guanine nucleotide-releasing factor 2
NCBI Official Symbol
RASGRF2  [Similar Products]
NCBI Official Synonym Symbols
GRF2; RAS-GRF2
  [Similar Products]
NCBI Protein Information
ras-specific guanine nucleotide-releasing factor 2; ras guanine nucleotide exchange factor 2
UniProt Protein Name
Ras-specific guanine nucleotide-releasing factor 2
UniProt Synonym Protein Names
Ras guanine nucleotide exchange factor 2
UniProt Gene Name
RASGRF2  [Similar Products]
UniProt Synonym Gene Names
GRF2; Ras-GRF2  [Similar Products]
UniProt Entry Name
RGRF2_HUMAN
NCBI Summary for RASGRF2
RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]
UniProt Comments for RASGRF2
RASGRF2: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.

Protein type: GEFs; GEFs, Ras

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: endoplasmic reticulum membrane; plasma membrane; cytosol

Molecular Function: calmodulin binding; Rho guanyl-nucleotide exchange factor activity

Biological Process: synaptic transmission; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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