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Rassf1 peptide

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Catalog # MBS425237
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
Rassf1 peptide
Product Name

Rassf1, Peptide

Also Known As

Rassf1 Immunizing Peptide

Product Synonym Names
RASSF1; Ras association (RalGDS/AF-6) domain family 1; AA536941; AU044980; NORE2A; RDA32; REH3P21; Rassf1A; Rassf1B; Rassf1C; 123F protein; Rassf1 (mouse)
Product Gene Name
Antibody/Peptide Pairs
Rassf1 peptide (MBS425237) is used for blocking the activity of Rassf1 antibody (MBS421391)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
270
Sequence
C-QAETEQKI KDYNGQ
Species Reactivity
Mouse, Rat
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of Rassf1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Rassf1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,193 Da
NCBI Official Full Name
ras association domain-containing protein 1 isoform 2
NCBI Official Synonym Full Names
Ras association (RalGDS/AF-6) domain family member 1
NCBI Official Symbol
Rassf1  [Similar Products]
NCBI Official Synonym Symbols
123F2; RDA32; NORE2A; REH3P21; Rassf1A; Rassf1B; Rassf1C; AA536941; AU044980
  [Similar Products]
NCBI Protein Information
ras association domain-containing protein 1
UniProt Protein Name
Ras association domain-containing protein 1
UniProt Synonym Protein Names
Protein 123F2
UniProt Gene Name
Rassf1  [Similar Products]
UniProt Entry Name
RASF1_MOUSE
UniProt Comments for Rassf1
RASSF1: Potential tumor suppressor. Required for death receptor- dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage. Interacts with MAP1S and XPA. Binds to the N-terminal of CDC20 during prometaphase. Binds to STK3/MST2 and STK4/MST1. Isoform A interacts with MOAP1 and E4F1. Recruited to the TNFRSF1A and TNFRSF10A complexes in response to their respective cognate ligand, after internalization. Can self-associate. Isoform A interacts with RSSF5 and probably associates with HRAS1 via a RSSF1 isoform A-RSSF5 heterodimer. Part of a complex with MDM2, DAXX, RASSF1 and USP7. Isoform A interacts (via C-terminus) with DAXX (via N-terminus); the interaction is independent of MDM2 and TP53. Isoform C or isoform H interacts (via N-terminus) with DAXX. Isoform A interacts (via N-terminus) with MDM2 (via C-terminus); the interaction is independent of TP53. Isoform A and isoform C are ubiquitously expressed in all tissues tested, however isoform A is absent in many corresponding cancer cell lines. Isoform B is mainly expressed in hematopoietic cells. 8 isoforms of the human protein are produced by alternative promoter.

Protein type: Tumor suppressor

Cellular Component: cytoplasm; cytoskeleton; microtubule; microtubule cytoskeleton; nucleus; plasma membrane

Molecular Function: identical protein binding; metal ion binding; protein binding; protein N-terminus binding

Biological Process: cell cycle; cell cycle arrest; positive regulation of protein ubiquitination; protein stabilization; Ras protein signal transduction; response to DNA damage stimulus; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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