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RBBP4 recombinant protein :: Histone-binding protein RBBP4 (RBBP4) Recombinant Protein

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Catalog # MBS1316857
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $840 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $920 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,125 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,150 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,240 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,245 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,390 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,410 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,660 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,875 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,160 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,235 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,255 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,335 +4 FREE 8GB USB
RBBP4 recombinant protein
Product Name

Histone-binding protein RBBP4 (RBBP4), Recombinant Protein

Full Product Name

Recombinant Bovine Histone-binding protein RBBP4 (RBBP4)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-425aa, Full Length of Mature Protein
Sequence
ADKEAAFDDA VEERVINEEY KIWKKNTPFL YDLVMTHALE WPSLTAQWLP DVTRPEGKDF SIHRLVLGTH TSDEQNHLVI ASVQLPNDDA QFDASHYDSE KGEFGGFGSV SGKIEIEIKI NHEGEVNRAR YMPQNPCIIA TKTPSSDVLV FDYTKHPSKP DPSGECNPDL RLRGHQKEGY GLSWNPNLSG HLLSASDDHT ICLWDISAVP KEGKVVDAKT IFTGHTAVVE DVSWHLLHES LFGSVADDQK LMIWDTRSNN TSKPSHSVDA HTAEVNCLSF NPYSEFILAT GSADKTVALW DLRNLKLKLH SFESHKDEIF QVQWSPHNET ILASSGTDRR LNVWDLSKIG EEQSPEDAED GPPELLFIHG GHTAKISDFS WNPNEPWVIC SVSEDNIMQV WQMAENIYND EDPEGSVDPE GQGS
3D Structure
ModBase 3D Structure for Q3MHL3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Bovine
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of RBBP4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RBBP4 recombinant protein
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for RBBP4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,656 Da
NCBI Official Full Name
histone-binding protein RBBP4
NCBI Official Synonym Full Names
RB binding protein 4, chromatin remodeling factor
NCBI Official Symbol
RBBP4  [Similar Products]
NCBI Protein Information
histone-binding protein RBBP4
UniProt Protein Name
Histone-binding protein RBBP4
UniProt Synonym Protein Names
Nucleosome-remodeling factor subunit RBAP48; Retinoblastoma-binding protein 4; RBBP-4
Protein Family
UniProt Gene Name
RBBP4  [Similar Products]
UniProt Synonym Gene Names
RBBP-4  [Similar Products]
UniProt Comments for RBBP4
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with RBBP4 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with RBBP4 and Liver
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