NP_001079131.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
75,881 Da
NCBI Official Full Name
amiloride-sensitive sodium channel subunit gamma-2
NCBI Official Synonym Full Names
sodium channel, non voltage gated 1 gamma subunit S homeolog
NCBI Official Synonym Symbols
pha1; enacg; scneg; scnn1g-a; scnn1g-b; ENaCgamma; gamma-ENaC; gamma XENaC; gamma2xENaC-A [Similar Products]
NCBI Protein Information
amiloride-sensitive sodium channel subunit gamma-2
UniProt Protein Name
Amiloride-sensitive sodium channel subunit gamma-2
UniProt Synonym Protein Names
Epithelial Na(+) channel subunit gamma-2; Gamma-2-ENaC; Gamma-2-NaCH; Nonvoltage-gated sodium channel 1 subunit gamma-2; SCNEG2
UniProt Synonym Gene Names
UniProt Comments for scnn1g-b
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
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