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DGAT1 recombinant protein :: Diacylglycerol O-acyltransferase 1 (DGAT1) Recombinant Protein

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Catalog # MBS1045342
Unit / Price DISCONTINUED
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DGAT1 recombinant protein
Product Name

Diacylglycerol O-acyltransferase 1 (DGAT1), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Diacylglycerol O-acyltransferase 1 (DGAT1), partial

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS1045342 COA
Sequence Positions
240-488aa; partial
Sequence
TVSYPDNLTY RDLYYFLFAP TLCYELNFPR SPRIRKRFLL RRILEMLFFT QLQVGLIQQW MVPTIQNSMK PFKDMDYSRI IERLLKLAVP NHLIWLIFFY WLFHSCLNAV AELMQFGDRE FYRDWWNSES VTYFWQNWNI PVHKWCIRHF YKPMLRRGSS KWMARTGVFL ASAFFHEYLV SVPLRMFRLW AFTGMMAQIP LAWFVGRFFQ GNYGNAAVWL SLIIGQPIAV LMYVHDYYVL NYEAPAAEA
OMIM
604900
3D Structure
ModBase 3D Structure for O75907
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of DGAT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DGAT1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,278 Da[Similar Products]
NCBI Official Full Name
diacylglycerol O-acyltransferase 1
NCBI Official Synonym Full Names
diacylglycerol O-acyltransferase 1
NCBI Official Symbol
DGAT1  [Similar Products]
NCBI Official Synonym Symbols
ARAT; DGAT; ARGP1; DIAR7
  [Similar Products]
NCBI Protein Information
diacylglycerol O-acyltransferase 1
UniProt Protein Name
Diacylglycerol O-acyltransferase 1
UniProt Synonym Protein Names
ACAT-related gene product 1; Acyl-CoA retinol O-fatty-acyltransferase (EC:2.3.1.76
UniProt Gene Name
DGAT1  [Similar Products]
UniProt Synonym Gene Names
AGRP1; DGAT; ARAT; Retinol O-fatty-acyltransferase  [Similar Products]
NCBI Summary for DGAT1
This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases. [provided by RefSeq, Jul 2013]
UniProt Comments for DGAT1
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Research Articles on DGAT1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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