View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Gpt active protein Catalog # MBS206318 Unit / Price 0.02 mg / $225 +1 FREE 8GB USB 0.1 mg / $350 +1 FREE 8GB USB 0.5 mg / $775 +1 FREE 8GB USB 5x0.5 mg / $3,205 +4 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Gpt, Active Protein Popular Item Full Product Name Gpt, 1-496aa, Rat, His tag, E Coli (Bioactivity Validated) Product Synonym Names Alanine aminotransferase 1 Product Gene Name Gpt active protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence MGSSHHHHHH SSGLVPRGSH MGSMASRVND QSQASRNGLK GKVLTLDTMN PCVRRVEYAV RGPIVQRALE LEQELRQGVK KPFTEVIRAN IGDAQAMGQR PITFFRQVLA LCVYPNLLSS PDFPEDAKRR AERILQACGG HSLGAYSISS GIQPIREDVA QYIERRDGGI PADPNNIFLS TGASDAIVTM LKLLVSGEGR ARTGVLIPIP QYPLYSAALA ELDAVQVDYY LDEERAWALD IAELRRALCQ ARDRCCPRVL CVINPGNPTG QVQTRECIEA VIRFAFKEGL FLMADEVYQD NVYAEGSQFH SFKKVLMEMG PPYSTQQELA SFHSVSKGYM GECGFRGGYV EVVNMDAEVQ KQMGKLMSVR LCPPVPGQAL MDMVVSPPTP SEPSFKQFQA ERQEVLAELA AKAKLTEQVF NEAPGIRCNP VQGAMYSFPQ VQLPLKAVQR AQELGLAPDM FFCLCLLEET GICVVPGSGF GQQEGTYHFR MTILPPMEKL RLLLEKLSHF HAKFTHEYS 3D Structure ModBase 3D Structure for P25409 Host E Coli Purity/Purification > 90% by SDS-PAGE Form/Format Liquid. In phosphate buffered saline pH 7.4 containing 10% glycerol Concentration 1mg/ml (determined by Absorbance at 280nm) (lot specific) Antigen Species Rat Tag Information His-tag Biological Activity Specific activity is > 60units/mg, and is defined as the amount of enzyme that cleaves 1umole of L-Alanine to L-Glutamate per minute at pH 7.5 at 37C. Preparation and Storage Can be stored at 4 degree C short term (1-2 weeks).For long term storage, aliquot and store at -20 degree C or -70 degree C.Avoid repeated freezing and thawing cycles. Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of Gpt active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Gpt active protein Gpt also known as Alanine aminotransferase 1, is a pyridoxal enzyme which catalyses the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate. The Gpt is widely distributed in various tissues from animals and even in some kind of plants. It is suggested that c-ALT is associated to the utilization of pyruvate in glycolysis and m-ALT is involved in the conversion of alanine to pyruvate for gluconeogenesis. Recombinant rat Gpt, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques Product Categories/Family for Gpt active protein Metabolism Applications Tested/Suitable for Gpt active protein SDS-PAGE SDS-Page of Gpt active protein TOP NCBI/Uniprot data below describe general gene information for Gpt. It may not necessarily be applicable to this product. NCBI GI # 13591961 NCBI GeneID 81670 NCBI Accession # NP_112301 [Other Products] NCBI GenBank Nucleotide # NM_031039.1 [Other Products] UniProt Primary Accession # P25409 [Other Products] UniProt Secondary Accession # Q4V7F7[Other Products] UniProt Related Accession # P25409[Other Products] Molecular Weight 57.5kDa (519aa) TOP NCBI Official Full Name alanine aminotransferase 1 NCBI Official Synonym Full Names glutamic--pyruvic transaminase NCBI Official Symbol Gpt [Similar Products] NCBI Official Synonym Symbols ALAT; Gpt1 [Similar Products] NCBI Protein Information alanine aminotransferase 1 UniProt Protein Name Alanine aminotransferase 1 UniProt Synonym Protein Names Glutamate pyruvate transaminase 1; GPT 1; Glutamic--alanine transaminase 1; Glutamic--pyruvic transaminase 1 Protein Family Alanine aminotransferase UniProt Gene Name Gpt [Similar Products] UniProt Synonym Gene Names Aat1; Gpt1; ALT1; GPT 1 [Similar Products] TOP NCBI Summary for Gpt human homolog is a cytosolic alanine aminotransferase [RGD, Feb 2006] TOP UniProt Comments for Gpt Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (). Research Articles on Gpt 1. Results indicate that AZD4619 increased alanine aminotransferase (ALT1) protein expression in a dose-dependent manner in human, but not in rat hepatocytes. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with Gpt active protein Reference Product PubMed Publications Got1 active protein >6 publications with Gpt and Got1 Got2 active protein >5 publications with Gpt and Got2 Idh2 active protein >2 publications with Gpt and Idh2 Idh1 active protein >2 publications with Gpt and Idh1 Agxt active protein >1 publications with Gpt and Agxt Glud1 active protein >1 publications with Gpt and Glud1 Pathways associated with Gpt active protein Products by Pathway Pathway Diagram 2-Oxocarboxylic Acid Metabolism Pathway antibodies 2-Oxocarboxylic Acid Metabolism Pathway Diagram 2-Oxocarboxylic Acid Metabolism Pathway antibodies 2-Oxocarboxylic Acid Metabolism Pathway Diagram Alanine And Aspartate Metabolism Pathway antibodies Alanine And Aspartate Metabolism Pathway Diagram Alanine, Aspartate And Glutamate Metabolism Pathway antibodies Alanine, Aspartate And Glutamate Metabolism Pathway Diagram Alanine, Aspartate And Glutamate Metabolism Pathway antibodies Alanine, Aspartate And Glutamate Metabolism Pathway Diagram Amino Acid Synthesis And Interconversion (transamination) Pathway antibodies Amino Acid Synthesis And Interconversion (transamination) Pathway Diagram Arginine Biosynthesis Pathway antibodies Arginine Biosynthesis Pathway Diagram Arginine Biosynthesis Pathway antibodies Arginine Biosynthesis Pathway Diagram Biosynthesis Of Amino Acids Pathway antibodies Biosynthesis Of Amino Acids Pathway Diagram Biosynthesis Of Amino Acids Pathway antibodies Biosynthesis Of Amino Acids Pathway Diagram Diseases associated with Gpt active protein Disease Name Pubmed Publications Liver Diseases Antibodies >967 publications with Gpt and Liver Diseases Poisoning Antibodies >397 publications with Gpt and Poisoning Hepatitis Antibodies >346 publications with Gpt and Hepatitis Drug-Related Side Effects and Adverse Reactions Antibodies >309 publications with Gpt and Drug-Related Side Effects and Adverse Reactions Chemical and Drug Induced Liver Injury Antibodies >302 publications with Gpt and Chemical and Drug Induced Liver Injury Necrosis Antibodies >273 publications with Gpt and Necrosis Disease Models, Animal Antibodies >178 publications with Gpt and Disease Models, Animal Liver Neoplasms Antibodies >177 publications with Gpt and Liver Neoplasms Liver Cirrhosis Antibodies >165 publications with Gpt and Liver Cirrhosis Inflammation Antibodies >152 publications with Gpt and Inflammation Organs/Tissues associated with Gpt active protein Organ/Tissue Name Pubmed Publications Liver Antibodies >1890 publications with Gpt and Liver Heart Antibodies >196 publications with Gpt and Heart Lung Antibodies >177 publications with Gpt and Lung Brain Antibodies >172 publications with Gpt and Brain Ovary Antibodies >81 publications with Gpt and Ovary Small Intestine Antibodies >47 publications with Gpt and Small Intestine Pancreas Antibodies >45 publications with Gpt and Pancreas Connective Tissue Antibodies >40 publications with Gpt and Connective Tissue Eye Antibodies >18 publications with Gpt and Eye Prostate Antibodies >14 publications with Gpt and Prostate TOP © 2006-24 MyBioSource.com. All rights reserved. Privacy Policy | Terms & Conditions Our Best Sellers CREB3L1 Antibody PNLIPRP2 Antibody Vitamin C Assay Kit GABARAPL1 Antibody Fumarylacetoacetase (FAH) ELISA Kit PIIICP ELISA Kit CCND3 ELISA Kit AFX Antibody ELISA Antibodies Secondary Antibodies Antigens Biochemicals cDNA Clones Kits Peptides Rec Proteins Protein Family Request a Quote Please fill out the form below and our representative will get back to you shortly. Catalog # MBS000000 Your E-mail (required) Ship to Country (required) United StatesAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegowinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCote DIvoireCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrance MetropolitanFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuineaGuinea-bissauGuyanaHaitiHeard and Mc Donald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKorea Democratic People Republic ofKorea Republic ofKuwaitKyrgyzstanLao People Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacauMacedonia The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia Federated States ofMoldova Republic ofMonacoMongoliaMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSeychellesSierra LeoneSingaporeSlovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSpainSri LankaSt. HelenaSt. Pierre and MiquelonSudanSurinameSvalbard and Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania United Republic ofThailandTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUnited States Minor Outlying IslandsUruguayUzbekistanVanuatuVatican City State (Holy See)VenezuelaViet NamVirgin Islands (British)Virgin Islands (U.S.)Wallis and Futuna IslandsWestern SaharaYemenYugoslaviaZaireZambiaZimbabwe Postal/Zip Code (required) Your Name Your Telephone Your Inquiries, Comments or Full Shipping Address (required) Contact Us Please fill out the form below and our representative will get back to you shortly. Inquiry for # MBS000000 Your Name Your Telephone Your E-mail (required) Your Inquiries or Comments