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HIV-1 pol Integrase Recombinant Protein

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Catalog # MBS142609
Unit / Price
  0.1 mg  /  $225 +1 FREE 8GB USB
  0.5 mg  /  $645 +1 FREE 8GB USB
  1 mg  /  $1,220 +1 FREE 8GB USB
HIV-1 pol Integrase recombinant protein
Product Name

HIV-1 pol Integrase, Recombinant Protein

Popular Item
Also Known As

Recombinant HIV-1 pol Integrase

Product Synonym Names
HIV-1 Integrase; HIV-1 Integrase Recombinant; HIV-1 Integrase
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
mfldgidkaq eehekyhsnw ramasdfnlp pvvakeivas cdkcqlkgea mhgqvdcspg iwqldcthle gkvilvavhv asgyieaevi paetgqetay filklagrwp vktihtdngs nftsttvkaa cwwagikqef gipynpqsqg viesmnkelk kiigqvrdqa ehlktavqma vfihnfkrkg giggysager ivdiiatdiq tkelqkqitk iqnfrvyyrd srdplwkgpa kllwkgegav viqdnsdikv vprrkakiir dygkqmagdd cvasrqdedh hhhhh
Host
E Coli
Specificity
Immunoreactive with all sera of HIV-1 infected individuals.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X & 50% Glycerol.
Sterile filtered colorless clear solution.
Concentration
4.55mg/1ml (lot specific)
Other Notes
Small volumes of HIV-1 pol Integrase recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
HIV-1 pol Integrase recombinant protein
Description: The E Coli derived 36 kDa recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the pol protein (intergrase) and fused with a six histidines tag.

Introduction: Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization, a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally, several host cellular proteins interact with integrase and may facilitate the integration process.
Applications Tested/Suitable for HIV-1 pol Integrase recombinant protein
ELISA (EIA), Western Blot (WB)
HIV-1 Integrase antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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