View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Jagged-1:Fc Active Protein Catalog # MBS635848 Unit / Price 0.01 mg / $510 +1 FREE 8GB USB 5x0.01 mg / $2,115 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Jagged-1:Fc, Active Protein Popular Item Full Product Name Jagged-1:Fc, Recombinant, Human (Protein Jagged-1, hJ1, CD339, JAG1) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Signal peptide and extracellu lar domain of human Jagged-1 (HJ1; CD339) (aa 1-1067) are fused at the C-terminus to the Fc portion of human IgG1. Host Human, HEK 293 cells Purity/Purification Highly Purified>90% (SDS-PAGE) Form/Format Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2. Biological Activity Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells. Preparation and Storage Short-term Storage: +4 degree CLong-term Storage: -20 degree CWorking aliquots are stable for up to 3 months when stored at -20 degree C. Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of Jagged-1:Fc active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Jagged-1:Fc active protein Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF). Product Categories/Family for Jagged-1:Fc active protein Molecular Biology; MB-Notch Proteins Molecular Weight ~150kD (SDS-PAGE)[Similar Products] TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP