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LTF recombinant protein :: Lactoferrin Recombinant Protein

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Catalog # MBS172026
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LTF recombinant protein
Product Name

Lactoferrin (LTF), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Lactoferrin, Holo

Product Synonym Names
LF, Lactotransferrin, LTF
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
gene 245480
92% (SDS-PAGE)
Appearance: Pink Powder
Human, full-length, glycosylated sequence without tags, signal peptides or other additions, expressed in Oryza sativa
> 1.0 mg/g Lactoferrin
Cas Number
0.88 mg lactoferrin/mg solid (elemental analsysis)
7.3 (1% Solution)
Bound Iron
1.4 mg/g lactoferrin.
< 1EU/mg
Reconstitute with PBS at up to 100mg/ml. Filter sterilize through a 0.2 micron filter. Store at 2-8 degree C for up to one week. Freeze at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
Preparation and Storage
At -20 degree C
Note: Protect from moisture.
Other Notes
Small volumes of LTF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
LTF recombinant protein
Custom preparations, technical support, bulk quantities and aliquoting available.

Cell Culture Grade Recombinant Human Lactoferrin: Recombinant Lactoferrin has been shown to enhance the growth of many cell types including intestinal cells, hybrioma cells, HEK, 3TC and osteoblasts. Our product's ability to enhance protein production has been tested in hybridoma and CHO cell lines. The optimum concentration for cell culture varies with the cell line.

Reported effective concentrations for hybridoma cell lines range from 4-500 mg/L. HEK 293, 100-200mg/L. CHO 250-750 mg/L. Other cell lines such as osteoblasts, show effective growth stimulation at concentrations below 1m/liter.

A Cell Culture Growth Factor: Lactoferrin can be added to cell culture media to promote cell growth, improve doubling times, increase cell viability and increase protein production.

An Iron Chelator: Lactoferrin has been used to deliver iron for certain cell culture applications.

A Vaccine Additive: Lactoferrin is sometimes used as an adjuvant for certain vaccines.

Human Health: Lactoferrin has several human health applications, including incorporation in clinical nutrition products, cosmetics, wound care formulations, infant formula and oral hygiene products.
NCBI/Uniprot data below describe general gene information for LTF. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
lactoferrin, partial
NCBI Official Synonym Full Names
NCBI Official Symbol
NCBI Official Synonym Symbols
LF; HLF2; GIG12; HEL110
  [Similar Products]
NCBI Protein Information
lactotransferrin; kaliocin-1; lactoferricin; lactoferroxin; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; epididymis luminal protein 110
UniProt Protein Name
UniProt Synonym Protein Names
Growth-inhibiting protein 12; TalalactoferrinCleaved into the following 5 chains:Lactoferricin-H; Lfcin-H; Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
GIG12; LF; Lactoferrin; Lfcin-H  [Similar Products]
UniProt Entry Name
NCBI Summary for LTF
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
UniProt Comments for LTF
LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter.

Protein type: Protease; Secreted, signal peptide; EC 3.4.21.-; Secreted

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule

Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; ferric iron binding; DNA binding; serine-type endopeptidase activity; iron ion binding

Biological Process: interaction with host; negative regulation of lipopolysaccharide-mediated signaling pathway; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; regulation of cytokine production; activation of NF-kappaB transcription factor; positive regulation of osteoblast differentiation; retinal homeostasis; negative regulation of viral genome replication; innate immune response in mucosa; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; negative regulation of viral reproduction; iron assimilation by chelation and transport; negative regulation of ATPase activity; negative regulation of apoptosis
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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