WP_011393225.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
46,398 Da
NCBI Official Full Name
phosphomethylpyrimidine synthase 3
NCBI Protein Information
thiamine biosynthesis protein ThiC
UniProt Protein Name
5-hydroxybenzimidazole synthase BzaA
UniProt Synonym Gene Names
UniProt Comments for thiC3
Together with BzaB, probably catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by M.thermoacetica (PubMed:26246619). Requires BzaB for catalytic activity, as BzaA alone displays no activity ().
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Pathways associated with thiC3 recombinant protein
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