NP_001035523.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
serine protease inhibitor Kazal-type 9
NCBI Official Synonym Full Names
serine peptidase inhibitor, Kazal type 9
NCBI Official Synonym Symbols
NCBI Protein Information
serine protease inhibitor Kazal-type 9
UniProt Protein Name
Serine protease inhibitor Kazal-type 9
UniProt Synonym Protein Names
Lymphoepithelial Kazal-type-related inhibitor 2
UniProt Synonym Gene Names
NCBI Summary for SPINK9
The protein encoded by this gene is a Kazal-type serine protease inhibitor that appears to specifically target kallikrein-related peptidase 5 (KLK5) in the palmo-plantar epidermis. KLK5 is an important initiator of skin desquamation, so the encoded protease inhibitor may regulate skin differentiation in the palms of hands and soles of feet. This cationic protein has also been shown to promote keratinocyte migration by activation of the epidermal growth factor receptor (EGFR). [provided by RefSeq, Dec 2015]
UniProt Comments for SPINK9
Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5.
Research Articles on SPINK9
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Products associated with SPINK9 recombinant protein
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