NP_001024335.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Protein SER-2, isoform a
NCBI Protein Information
Protein SER-2
UniProt Protein Name
Tyramine receptor ser-2
UniProt Entry Name
SER2_CAEEL
UniProt Comments for ser-2
Function: G-protein coupled receptor for tyramine, a known neurotransmitter and neuromodulator and direct precursor of octopamine. The rank order of potency is tyramine > octopamine > dopamine > serotonin > epinephrine = norepinephrine. Ref.2
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: The different isoforms are expressed in specific, but overlapping sets of sensory, inter- and motor neurons, including AIY, AIZ and RIA interneurons. They are also expressed in pharyngeal cells, head muscles and excretory gland cells. Ref.3
Disruption phenotype: A loss-of-function mutation does not affect the development of AIY interneurons, or lead to egg-laying or any other behavioral defects. Ref.3
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Research Articles on ser-2
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Organs/Tissues associated with ser-2 recombinant protein
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