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anti-RHEB antibody :: Rheb Antibody

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Catalog # MBS854642
Unit / Price
  0.05 mg  /  $225 +1 FREE 8GB USB
Product Name

Rheb, Antibody

Also Known As

Rheb Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
184
OMIM
601293
3D Structure
ModBase 3D Structure for Q15382
Other Notes
Small volumes of anti-RHEB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot of anti-RHEB antibody
Western blot analysis of protein extracts from 293 cells overexpressing a mouse Rheb cDNA. The primary antibody was diluted 1:2000 before applied to the blotting membrane. (Right Panel: a schematic illustration of 17 mTOR signaling pathway.)
anti-RHEB antibody Western Blot (WB) image
Testing Data of anti-RHEB antibody
anti-RHEB antibody Testing Data image
NCBI/Uniprot data below describe general gene information for RHEB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,497 Da
NCBI Official Full Name
GTP-binding protein Rheb
NCBI Official Synonym Full Names
Ras homolog, mTORC1 binding
NCBI Official Symbol
NCBI Official Synonym Symbols
RHEB2
  [Similar Products]
NCBI Protein Information
GTP-binding protein Rheb
UniProt Protein Name
GTP-binding protein Rheb
UniProt Synonym Protein Names
Ras homolog enriched in brain
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
RHEB2  [Similar Products]
NCBI Summary for RHEB
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]
UniProt Comments for RHEB
Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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