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RHOQ cdna clone

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Catalog # MBS1276587
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
RHOQ cdna clone
Product Name

RHOQ, cDNA Clone

Popular Item
Full Product Name

RHOQ cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ATGGCTCACG GGCCCGGCGC GCTGATGCTC AAGTGCGTGG TGGTCGGCGA CGGGGCGGTG GGCAAGACGT GCCTACTCAT GAGCTATGCC AACGACGCCT TCCCGGAGGA GTACGTGCCC ACCGTCTTCG ACCACTACGC AGTCAGCGTC ACCGTGGGGG GCAAGCAGTA CCTCCTAGGA CTCTATGACA CGGCCGGACA GGAAGACTAT GACCGTCTGA GGCCTTTATC TTACCCAATG ACCGATGTCT TCCTTATATG CTTCTCGGTG GTAAATCCAG CCTCATTTCA AAATGTGAAA GAGGAGTGGG TACCGGAACT TAAGGAATAC GCACCAAATG TACCCTTTTT ATTAATAGGA ACTCAGATTG ATCTCCGAGA TGACCCCAAA ACTTTAGCAA GACTGAATGA TATGAAAGAA AAACCTATAT GTGTGGAACA AGGACAGAAA CTAGCAAAAG AGATAGGAGC ATGCTGCTAT GTGGAATGTT CAGCTTTAAC CCAGAAGGGA TTGAAGACTG TTTTTGATGA GGCTATCATA GCCATTTTAA CTCCAAAGAA ACACACTGTA AAAAAAAGAA TAGGATCAAG ATGTATAAAC TGTTGTTTAA TTACGTGA
OMIM
605857
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of RHOQ cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for RHOQ. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,659 Da
NCBI Official Full Name
Homo sapiens ras homolog gene family, member Q, mRNA
NCBI Official Synonym Full Names
ras homolog family member Q
NCBI Official Symbol
NCBI Official Synonym Symbols
ARHQ; TC10; TC10A; RASL7A; HEL-S-42
  [Similar Products]
NCBI Protein Information
rho-related GTP-binding protein RhoQ
UniProt Protein Name
Rho-related GTP-binding protein RhoQ
UniProt Synonym Protein Names
Ras-like protein TC10; Ras-like protein family member 7A
UniProt Gene Name
UniProt Synonym Gene Names
ARHQ; RASL7A; TC10  [Similar Products]
UniProt Entry Name
RHOQ_HUMAN
NCBI Summary for RHOQ
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]
UniProt Comments for RHOQ
RHOQ: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein, monomeric; G protein; Motility/polarity/chemotaxis; G protein, monomeric, Rho

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: actin filament; cytosol; plasma membrane

Molecular Function: GBD domain binding; GTPase activity; profilin binding

Biological Process: cellular response to insulin stimulus; cortical actin cytoskeleton organization and biogenesis; GTP metabolic process; insulin receptor signaling pathway; positive regulation of filopodium formation; positive regulation of glucose import; positive regulation of transcription from RNA polymerase II promoter; regulation of actin cytoskeleton organization and biogenesis; regulation of small GTPase mediated signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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