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RK-33 biochemical

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Catalog # MBS846413
Unit / Price
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  5 mg  /  $215 +1 FREE 8GB USB
  25 mg  /  $710 +1 FREE 8GB USB
Structure
Product Name

RK-33, Biochemical

Full Product Name

RK-33

Product Synonym Names
3; 7-dihydro-3; 7-bis[ (4-methoxyphenyl) methyl]-2H-diimidazo[4; 5-d:4'; 5'-f][1; 3]diazepin-2-one
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
>=98% by HPLC
Form/Format
Crystalline solid
Salt Form
No
Molecular Formula
C23H20N6O3
CAS Number
1070773-09-9
Cell-Permeable
Yes
Reconstitution
DMSO (>20 mg/ml)
SMILES
COC1=CC=C(C=C1)CN2C=NC3=C2N=CN=C4C3=NC(=O)N4CC5=CC=C(C=C5)OC
InChi
InChI=1S/C23H20N6O3/c1-31-17-7-3-15(4-8-17)11-28-14-26-19-20-22(25-13-24-21(19)28)29(23(30)27-20)12-16-5-9-18(32-2)10-6-16/h3-10,13-14H,11-12H2,1-2H3
InChi Key
COUMZXFUZDBRCZ-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Other Notes
Small volumes of RK-33 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RK-33 biochemical
RK-33 is an inhibitor of DEAD box 3 (DDX3); an ATP-dependent RNA helicase. RK-33 inhibits the growth of lung cancer cells that overexpress DDX3 (IC50s = 4.4-8.4 uM) but is less effective in cells with low DDX3 expression (IC50 > 25 uM). It also promotes radiation sensitization in cells overexpressing DDX3. RK-33 in combination with radiation induces tumor regression in multiple animal models of lung cancer.

Structure of RK-33 biochemical
RK-33 biochemical Structure image
Molecular Weight
428.45
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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