NP_079221.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
70,144 Da
NCBI Official Full Name
recQ-mediated genome instability protein 1
NCBI Official Synonym Full Names
RecQ mediated genome instability 1
NCBI Protein Information
recQ-mediated genome instability protein 1; BLM-associated protein 75 kDa; BLM-associated polypeptide, 75 kDa; RMI1, RecQ mediated genome instability 1, homolog; homolog of yeast RecQ-mediated genome instability 1 (RMI1)
UniProt Protein Name
RecQ-mediated genome instability protein 1
UniProt Synonym Protein Names
BLM-associated protein of 75 kDa; BLAP75; FAAP75
UniProt Synonym Gene Names
UniProt Entry Name
RMI1_HUMAN
NCBI Summary for RMI1
RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM, Mar 2008]
UniProt Comments for RMI1
RMI1: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. Belongs to the RMI1 family.
Protein type: DNA repair, damage
Chromosomal Location of Human Ortholog: 9q21.32
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: multicellular organism growth; response to glucose stimulus; DNA replication; glucose homeostasis; reduction of food intake in response to dietary excess
Research Articles on RMI1
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Products associated with RMI1 elisa kit
Pathways associated with RMI1 elisa kit
Diseases associated with RMI1 elisa kit
Organs/Tissues associated with RMI1 elisa kit
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