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rmMIG recombinant protein :: MIG Recombinant Protein

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Catalog # MBS142044
Unit / Price
  0.005 mg  /  $140 +1 FREE 8GB USB
  0.02 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $2,665 +3 FREE 8GB USB
rmMIG recombinant protein
Product Name

MIG (rmMIG), Recombinant Protein

Also Known As

Recombinant Mouse MIG (CXCL9)

Product Synonym Names
MIG Mouse; MIG Mouse Recombinant (CXCL9); Small inducible cytokine B9; CXCL9; Gamma interferon-induced monokine; MIG; chemokine (C-X-C motif) ligand 9; CMK; Humig; SCYB9; crg-10; M119; monokine induced by gamma-interferon
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
126
Sequence
The sequence of the first five N-terminal amino acids was determined and was found to be, Thr-Leu-Va l-Ile-Arg
3D Structure
ModBase 3D Structure for P18340
Host
E Coli
Purity/Purification
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
The CXCL9 was lyophilized from a concentrated (1mg/ml) solution in water containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility
It is recommended to reconstitute the lyophilized MIG in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
The Activity is calculated by the ability to chemoattract Human lymphocytes using a concentration of 0.1-1ng/ml corresponding to a Specific Activity of 1,000,000-10,000,000IU/mg.
Preparation and Storage
Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL9 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Other Notes
Small volumes of rmMIG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
rmMIG recombinant protein
Description: MIG (monokine induced by gamma-interferon) Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 105 amino acids and having a molecular mass of 12208 Dalton. The MIG is purified by proprietary chromatographic techniques.

Introduction: Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-?. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.
NCBI/Uniprot data below describe general gene information for rmMIG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,444 Da
NCBI Official Full Name
C-X-C motif chemokine 9
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 9
NCBI Official Symbol
Cxcl9  [Similar Products]
NCBI Official Synonym Symbols
CMK; Mig; MuMIG; Scyb9; crg-10; BB139920
  [Similar Products]
NCBI Protein Information
C-X-C motif chemokine 9; M119; gamma interferon-induced monokine; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; protein m119; small inducible cytokine B subfamily (Cys-X-Cys), member 9; small-inducible cytokine B9
UniProt Protein Name
C-X-C motif chemokine 9
UniProt Synonym Protein Names
Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; MIG; MuMIG; Protein m119; Small-inducible cytokine B9
UniProt Gene Name
Cxcl9  [Similar Products]
UniProt Synonym Gene Names
Mig; Scyb9; MIG; MuMIG  [Similar Products]
UniProt Entry Name
CXCL9_MOUSE
UniProt Comments for rmMIG
CXCL9: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: CXCR3 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; chemotaxis; inflammatory response; defense response to virus; positive regulation of myoblast differentiation; regulation of cell proliferation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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