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RORC elisa kit :: Human RAR-related orphan receptor C ELISA Kit

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Catalog # MBS911044
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Typical Testing Data/Standard Curve (for reference only)
Product Name

RAR-related orphan receptor C (RORC), ELISA Kit

Popular Item
Full Product Name

Human Nuclear receptor ROR-gamma, RORC ELISA Kit

Product Synonym Names
Human Nuclear receptor ROR-gamma (RORC) ELISA kit; MGC129539; NR1F3; RORG; RZR-GAMMA; RZRG; TOR; RAR-related orphan receptor C; isoform a; RAR-related orphan receptor gamma; nuclear receptor ROR-gamma; retinoic acid-binding receptor gamma; retinoid-rela; RAR-related orphan receptor C
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS911044 Testing Data
3D Structure
ModBase 3D Structure for P51449
Species Reactivity
This assay has high sensitivity and excellent specificity for detection of human RORC. No significant cross-reactivity or interference between human RORC and analogues was observed.
Serum, plasma, tissue homogenates, cell lysates.
Assay Type
Detection Range
12.5 pg/ml -800 pg/ml.
3.12 pg/ml.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of RORC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for RORCpurchase
MBS911044 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the RAR-related orphan receptor C (RORC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RORC. The ELISA analytical biochemical technique of the MBS911044 kit is based on RORC antibody-RORC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RORC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RORC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
RORC elisa kit
Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for RORC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RORC present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RORC is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RORC bound in the initial step. The color development is stopped and the intensity of the color is measured.

Typical Testing Data/Standard Curve (for reference only) of RORC elisa kit
RORC elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS911044. Click to request current manual
NCBI/Uniprot data below describe general gene information for RORC. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,195 Da
NCBI Official Full Name
nuclear receptor ROR-gamma isoform b
NCBI Official Synonym Full Names
RAR-related orphan receptor C
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
nuclear receptor ROR-gamma; nuclear receptor RZR-gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; RAR-related orphan receptor C, isoform a; RAR-related orphan nuclear receptor variant 2; nuclear receptor subfamily 1 group F member 3
UniProt Protein Name
Nuclear receptor ROR-gamma
UniProt Synonym Protein Names
Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR-related orphan receptor C; Retinoid-related orphan receptor-gamma
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NR1F3; RORG; RZRG  [Similar Products]
UniProt Entry Name
NCBI Summary for RORC
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for RORC
RORC: Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock. Belongs to the nuclear hormone receptor family. NR1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor; Nuclear receptor

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; ligand-dependent nuclear receptor activity; DNA binding; zinc ion binding; sequence-specific DNA binding; oxysterol binding; steroid hormone receptor activity; transcription factor activity

Biological Process: Peyer's patch development; transcription initiation from RNA polymerase II promoter; intracellular receptor-mediated signaling pathway; T-helper cell differentiation; regulation of fat cell differentiation; positive regulation of transcription, DNA-dependent; T cell differentiation in the thymus; positive regulation of circadian rhythm; regulation of gamma-delta T cell differentiation; lymph node development; protein amino acid phosphorylation; xenobiotic metabolic process; regulation of steroid metabolic process; gene expression; steroid hormone mediated signaling; circadian regulation of gene expression
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Organs/Tissues associated with RORC elisa kit
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >5 publications with RORC and Kidney
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