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RPL5 recombinant protein :: 60S ribosomal protein L5 (RPL5) Recombinant Protein

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Catalog # MBS950645
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $495 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $645 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $660 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $725 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $880 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $885 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $990 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,085 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,120 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,265 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,565 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,665 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,830 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,595 +3 FREE 8GB USB
RPL5 recombinant protein
Product Name

60S ribosomal protein L5 (RPL5), Recombinant Protein

Full Product Name

Recombinant Rabbit 60S ribosomal protein L5 (RPL5)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-101aa, Full length protein
Sequence
GFVKVVKNKA YFKRYQVKFR RRREGKTDYY ARKRLVIQDK NKYNTPAHAA IRENPVYEKK PKREVKKKRW NRPKMSLAQK KDRVAQKKAS FLRAQERAAE S
3D Structure
ModBase 3D Structure for P19949
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rabbit
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of RPL5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RPL5 recombinant protein
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
NCBI/Uniprot data below describe general gene information for RPL5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,228 Da
NCBI Official Full Name
60S ribosomal protein L5
NCBI Official Symbol
NCBI Protein Information
60S ribosomal protein L5
UniProt Protein Name
60S ribosomal protein L5
Protein Family
UniProt Gene Name
UniProt Comments for RPL5
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs. It also couples ribosome biogenesis to p53/TP53 activation. As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53. Interacts with RRP1B.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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