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RRAGA elisa kit :: Human Ras-related GTP binding A ELISA Kit

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Catalog # MBS9334409
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
RRAGA elisa kit
Product Name

Ras-related GTP binding A (RRAGA), ELISA Kit

Also Known As

Human Ras-related GTP-binding protein A, RRAGA ELISA Kit

Product Synonym Names
Human Ras-related GTP-binding protein A (RRAGA) ELISA kit; FIP-1; FIP1; RAGA; Ras-related GTP-binding protein; adenovirus E3-14.7K interacting protein 1; Ras-related GTP binding A
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
612194
3D Structure
ModBase 3D Structure for Q7L523
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of RRAGA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forRRAGApurchase
MBS9334409 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ras-related GTP binding A (RRAGA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RRAGA. The ELISA analytical biochemical technique of the MBS9334409 kit is based on RRAGA antibody-RRAGA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RRAGA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RRAGA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for RRAGA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,566 Da
NCBI Official Full Name
ras-related GTP-binding protein A
NCBI Official Synonym Full Names
Ras-related GTP binding A
NCBI Official Symbol
RRAGA  [Similar Products]
NCBI Official Synonym Symbols
FIP1; RAGA; FIP-1
  [Similar Products]
NCBI Protein Information
ras-related GTP-binding protein A; rag A; adenovirus E3-14.7K interacting protein 1; adenovirus E3 14.7 kDa-interacting protein 1
UniProt Protein Name
Ras-related GTP-binding protein A
UniProt Synonym Protein Names
Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1
UniProt Gene Name
RRAGA  [Similar Products]
UniProt Synonym Gene Names
Rag A; RagA  [Similar Products]
UniProt Entry Name
RRAGA_HUMAN
UniProt Comments for RRAGA
RRAGA: Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF- alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein. Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain. Belongs to the GTR/RAG GTP-binding protein family.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 9p22.1

Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; lysosomal membrane; lysosome; cytoplasm; nucleus

Molecular Function: GTPase activity; protein binding; GDP binding; protein homodimerization activity; GTP binding; protein heterodimerization activity; phosphoprotein binding

Biological Process: cell death; apoptosis; metabolic process; virus-host interaction; regulation of autophagy; positive regulation of cytolysis; cellular response to starvation; positive regulation of TOR signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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